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  1. Light-Evoked Synaptic Activity of Retinal Ganglion and Amacrine Cells is Regulated in Developing Mouse Retina

    This paper by Q. He, Wang P and Ning Tian characterizes the developmental profiles of the light evoked excitatory and inhibitory synaptic inputs from ON and OFF synaptic pathways in the retina, the light evoked synaptic outputs and the sensitivity of the light evoked synaptic inputs and outputs to light deprivation of retinal ganglion cells […]

    Jun 27, 2011 — Read more 1 Comment
  2. A Photographers Visit to the Moran Eye Center

    A friend of Webvision, renaissance man and photographer extraordinaire, Duncan Davidson visited us at the Moran Eye Center and hung out for a day of science while we performed experiments.  Duncan documented some of the work we did that day in the lovely video he posted to Vimeo above.  You have quite possibly seen Duncan’s […]

    Jun 25, 2011 — Read more No Comments
  3. Iris Sphere

    We present to you for your Friday viewing, another entry in the Art of Vision category, an artistic image of a montage of the iris and pupil from James Gilman of the Moran Eye Center

    Jun 22, 2011 — Read more No Comments
  4. Astrocyte/Blood Vessel Relationships

    Another image sent to us by Dr. Nicolás Cuenca of the University of Alicante, created by Laura Fernández-Sánchez and Nicolás Cuenca, is the winning picture of the 2010 European Vision Research image competition.

    Jun 20, 2011 — Read more No Comments
  5. Notable Paper: Virally Delivered Channelrhodopsin-2 Safely and Effectively Restores Visual Function in Multiple Mouse Models of Blindness

    This truly groundbreaking paper by M Mehdi Doroudchi, Kenneth P Greenberg, Jianwen Liu, Kimberly A Silka, Edward S Boyden, Jennifer A Lockridge, A Cyrus Arman, Ramesh Janani, Shannon E Boye, Sanford L Boye, Gabriel M Gordon, Benjamin C Matteo, Alapakkam P Sampath, William W Hauswirth and Alan Horsager demonstrates that channelrhodopsin-2, a cation channel from […]

    Jun 16, 2011 — Read more No Comments
  6. Stargardt’s Disease angiogram

    Venous phase fluorescein sodium angiogram of a dark choroid in Stargardt’s disease or fundus flavimaculatus.  Stargart’s Disease is a progressive retinal degenerative disease caused by mutations in one of 3 genes, ABCA4, ELOVL4 or PROM1.  The disease is a form of juvenile onset macular degeneration affecting the retinal pigmented epithelium (RPE).  The disease onset and progression is […]

    Jun 15, 2011 — Read more 1 Comment
  7. Notable Paper: UNC119 is Required for G Protein Trafficking in Sensory Neurons

      Photoreceptors are specialized cells that elaborate a cilium which becomes the inner and outer segments of the photoreceptor that house photopigments (a beautiful TEM image of a photoreceptor cilium and its inner/outer segment can be seen here)….  

    Jun 14, 2011 — Read more No Comments
  8. Cone Opsin Determines The Time Course of Cone Photoreceptor Degeneration in Leber Congenital Amaurosis

    It is been long known that ventral and central cones degenerate more rapidly than dorsal cones in retinoid-deprived LCA (Leber’s Congenital Amaurosis) models.  This paper in PNAS by Tao Zhang, Wolfgang Baehr…

    Jun 13, 2011 — Read more No Comments
  9. 100 Papers You Should Read: Synaptic Relationships in the Plexiform Layers of Carp Retina

    This is the third paper in the category, 100 Papers You Should Read (in vision science). This paper, Synaptic Relationships in the Plexiform Layers of Carp Retina by Paul Witkovsky and John Dowling along with a previous one, Dowling and Boycott, 1966, began to set the stage for investigations into the circuitry of the inner plexiform […]

    Jun 10, 2011 — Read more No Comments
  10. Alan Horsager speaks at TEDx

    I was talking with Dr. Alan Horsager the other day and was pleased to find out that he gave a brief talk at TEDx USC.  His talk was on a set of technologies and an approach that we in the Marclab are collaborating…

    Jun 6, 2011 — Read more No Comments