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  1. Seminar: Cholesterol and the Retina: Twists and Turns of Biology and Pathobiology

    Steven J. Fliesler, UB Distinguished Professor and Chair of Ophthalmology at University of Buffalo/State University of New York (SUNY) will be delivering a seminar on Cholesterol and the Retina: Twists and Turns of Biology and Pathobiology on Thursday, October 8th at 11:30am  in the the Moran Eye Center auditorium. Abstract: Cholesterol is a ubiquitous component of almost all cellular membranes in higher eukaryotes, and […]

    Sep 26, 2015 — Read more No Comments
  2. EMT And Myofibroblast Generation In An Injured Lens

    Shizuya Saika, Professor and Chairman of Wakayama Medical University will be delivering a seminar on EMT and myofibroblast generation in an injured lens: modulation of TGFb/Smad signal by extracellular matrix on Tuesday, October 6th at Noon  in the the Moran Eye Center auditorium. Abstract: EMT and myofibroblast appears in the fibrotic tissues that are undergoing wound healing process. In the eye it is […]

    Sep 23, 2015 — Read more No Comments
  3. Missense variant in CST3 Exerts Recessive Effect On Susceptibility to AMD

    There is an interesting paper out demonstrating that CST3 exerts a recessive effect on susceptibility to AMD.  Cystatin C is a potent inhibitor of cysteine proteinases expressed by many tissues and in the eye, it is highly expressed by the retinal pigment epithelium (RPE). The team led by Luminita Paraoan recently reported data identifying a polymorphism in the […]

    Sep 22, 2015 — Read more No Comments
  4. Bruch’s Membrane

    Bruch’s membrane is a highly specialized and multi-laminar structure in our retinas that forms the basis for mediating interactions between the retinal pigment epithelium and blood flow from the choroid.  I’ve not seen many good images online, so figured this image from mouse would be a good addition showing the relationship of the basal surface […]

    Sep 5, 2015 — Read more No Comments