Skip to content

  1. Retinoid Receptors Trigger Neuritogenesis in Retinal Degenerations

    This paper by Y Lin, BW Jones, A Liu, JF Tucker, K Rapp, L Luo, W Baehr, PS Bernstein, CB Watt, JH Yang, MV Shaw and RE Marc examines the neuronal sprouting or neuritogenesis components of retinal remodeling found in retinal degenerative disease and describes a control process for retinoid X receptors (RXRs) in neuritogenesis. 

    Oct 11, 2011 — Read more 1 Comment
  2. Notable Paper: Increased Expression of Multifunctional Serine Protease, HTRA1, in Retinal Pigment Epithelium Induces Polypoidal Choroidal Vasculopathy

    Efforts to explore chromosome 10q26, a major candidate region associated with age-related macular degeneration (AMD) have proven difficult and controversial.  This particular region of interest is two neighboring genes, ARMS2 and HTRA1.  However, efforts in trying to explore the functional involvement of either HTRA1 or ARMS2 in AMD have proven to be difficult and have […]

    Aug 18, 2011 — Read more No Comments
  3. Notable Paper: Retinal Remodeling in the Tg P347L Rabbit, a Large-Eye Model of Retinal Degeneration

    This paper is the result of a collaborative effort between Bryan William Jones, Mineo Kondo and Hiroko Terasaki, Carl Watt, Kevin Rapp, James Anderson, Yanhua Lin, Maggie Shaw, Jia-Hui Yang and Robert Marc. This work presents a substantial advance in models of Retinitis pigmentosa (RP), an set of inherited blinding diseases characterized by progressive loss of retinal photoreceptors.  

    Aug 4, 2011 — Read more 1 Comment
  4. Rod Photoreceptor TEM

    May 11, 2011 — Read more 2 Comments
  5. Bipolar Cell “Accessory ON” Input to Amacrine Cells in the OFF Inner Plexiform Layer

    May 4, 2011 — Read more No Comments