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  1. New Webvision Chapter: Retinal Degeneration, Remodeling and Plasticity

    We have a new Webvision chapter on Retinal Degeneration, Remodeling and Plasticity! Check it out here.

    Jun 1, 2015 — Read more No Comments
  2. Interesting Paper: Gene Expression Changes Within Müller Glial Cells in Retinitis Pigmentosa

    Retinal degenerations are accompanied by retinal remodeling events.  These events alter the structure and function of the retina and involve to a large extent, Müller cells which seem to serve as pathways for neuronal migration.  This paper by Karin Roesch, Michael B. Stadler and Constance L. Cepko looks at gene expression changes in the Müller cells, one […]

    Nov 13, 2012 — Read more No Comments
  3. Functional and Anatomical Remodeling in Human Retinal Detachment

    This manuscript by Clairton F de Souza, Michael Kalloniatis, Philip J Polkinghorne, Charles N J McGhee and Monica L Acosta examined retinal remodeling in response to a form of retinal detachment.  Rhegmatogenous retinal detachment.  The authors describe the changes observed and note that retinal plasticity is acute and likely occurs quickly enough that it may explain persistent […]

    Jun 28, 2012 — Read more No Comments
  4. Notable Paper: Network Deficiency Exacerbates Impairment in a Mouse Model of Retinal Degeneration

    This paper by Christopher W. Yee, Abduqodir H. Toychiev and Botir T. Sagdullaev examines the role that neural oscillations play in normal and pathological states.  In a neurodegenerative model of retinitis pigmentosa, the authors examined the activity of neural networks in the rd1 mouse model and compared that activity to the wild type.  

    Apr 1, 2012 — Read more No Comments
  5. Retinoid Receptors Trigger Neuritogenesis in Retinal Degenerations

    This paper by Y Lin, BW Jones, A Liu, JF Tucker, K Rapp, L Luo, W Baehr, PS Bernstein, CB Watt, JH Yang, MV Shaw and RE Marc examines the neuronal sprouting or neuritogenesis components of retinal remodeling found in retinal degenerative disease and describes a control process for retinoid X receptors (RXRs) in neuritogenesis. 

    Oct 11, 2011 — Read more 1 Comment
  6. Notable Paper: Retinal Remodeling in the Tg P347L Rabbit, a Large-Eye Model of Retinal Degeneration

    This paper is the result of a collaborative effort between Bryan William Jones, Mineo Kondo and Hiroko Terasaki, Carl Watt, Kevin Rapp, James Anderson, Yanhua Lin, Maggie Shaw, Jia-Hui Yang and Robert Marc. This work presents a substantial advance in models of Retinitis pigmentosa (RP), an set of inherited blinding diseases characterized by progressive loss of retinal photoreceptors.  

    Aug 4, 2011 — Read more 1 Comment
  7. Visual Restoration And Circuitry-Retinal Sheet Transplants To Rats With Retinal Degeneration

    May 4, 2011 — Read more No Comments
  8. CaMKII Signaling is Contributive to Neuritogenesis in Light-Induced Retinal Degeneration

    May 2, 2011 — Read more No Comments