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  1. New Webvision Chapter: Retinal Degeneration, Remodeling and Plasticity

    We have a new Webvision chapter on Retinal Degeneration, Remodeling and Plasticity! Check it out here.

    Jun 1, 2015 — Read more No Comments
  2. Müller Cell Metabolic Chaos During Degeneration

    This abstract was presented today at the 2015 Association for Research in Vision and Opthalmology (ARVO) meetings in Denver, Colorado by  Rebecca L. Pfeiffer, Bryan W. Jones and Robert E. Marc. Purpose: Müller cells (MCs) play a critical role in glutamate (E) metabolism and carbon skeleton cycling in retina. MCs demonstrate changes in metabolism and morphology during retinal degeneration. The timing, […]

    May 7, 2015 — Read more No Comments
  3. Moran Eye Center Researcher Robert E. Marc: 2014 Paul Kayser Award In Retina Research

    Our colleague and Director of Research at the University of Utah‘s Moran Eye Center, Robert E. Marc, Ph.D. has been named by the International Society for Eye Research as a recipient of the Paul Kayser International Award in Retina Research.  The award will be presented to Dr. Marc during the 2014 ISER Biennial Meeting of […]

    Jun 25, 2014 — Read more No Comments
  4. A Synaptic Basis for Small World Network Design in the ON Inner Plexiform Layer of the Rabbit Retina

    This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by J Scott Lauritzen, Noah T. Nelson, Crystal L. Sigulinsky, Nathan Sherbotie, John Hoang, Rebecca L. Pfeiffer, James R. Anderson, Carl B. Watt, Bryan W. Jones and Robert E. Marc. Purpose: Converging evidence suggests that large- and intermediate-scale neural networks throughout the nervous system exhibit small world’ […]

    May 6, 2014 — Read more No Comments
  5. Metabolic Changes Associated With Müller Cells In A Transgenic Rabbit Model Of Retinal Degeneration

    This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by  Rebecca L. Pfeiffer, Bryan W. Jones and Robert E. Marc. Purpose: Müller cells play a central role in retinal metabolism via the glutamate cycle. During retinal degeneration Müller cells are among the first to demonstrate changes, reflected […]

    May 4, 2014 — Read more No Comments
  6. Retinal Metabolic Response to Cigarette Smoke

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Seattle, Washington by Alexandra D. Butler, William D. Ferrell, Alex Woodell, Carl Atkinson, Baerbel Rohrer, Robert E. Marc and Bryan W. Jones. 

    May 7, 2013 — Read more No Comments
  7. Constructive Retinal Plasticity After Selective Ablation of the Photoreceptors

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Seattle, Washington by Corinne N. Beier, Bryan W. Jones, Philip Huie, Yannis M. Paulus, Daniel Lavinsky, Loh-Shan B. Leung, Hiroyuki Nomoto,  Robert E. Marc, Daniel V. Palanker, and Alexander Sher.

    May 7, 2013 — Read more No Comments
  8. Sparse Network Principles of GABAergic Amacrine Cell Heterocellular Coupling

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Seattle, Washington by Crystal L. Sigulinsky, J. Scott Lauritzen, John V. Hoang, Carl B. Watt, Bryan W. Jones, James R. Anderson, Shoeb Mohammed and Robert E. Marc.

    May 6, 2013 — Read more No Comments
  9. Tiered Cross-Class Bipolar Cell Gap Junctional Coupling in the Rabbit Retina

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Seattle, Washington by J. Scott Lauritzen, John V. Hoang, Crystal Sigulinsky, Bryan W. Jones, James R. Anderson, Carl B. Watt, Shoeb Mohammed and Robert E. Marc.

    May 6, 2013 — Read more No Comments
  10. Pure Feedforward Amacrine Cells

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Seattle, Washington by Robert E. Marc, Felix R. Vazquez-Chona, John V. Hoang, Crystal Sigulinsky, Carl B. Watt, Bryan W. Jones, James R. Anderson and J. Scott Lauritzen. 

    May 6, 2013 — Read more No Comments
  11. Retinal Remodeling in a Rat Model of the Smith-Lemli-Opitz Syndrome (SLOS)

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Seattle, Washington by Steven J. Fliesler, Christopher C. Goulah, W. Drew Ferrell, Robert E. Marc and Bryan W. Jones.

    May 5, 2013 — Read more No Comments
  12. Building Retinal Connectomes

    There has been quite a bit of discussion of connectomes in the last while with President Obama’s new BRAIN initiative.  It is important to consider some of the requirements of obtaining a true synapse level wiring map in the brain as many are articulating from this initiative.  While there are new technologies that will be […]

    Apr 22, 2013 — Read more No Comments
  13. Notable Paper: On Cone Bipolar Cell Axonal Synapses In The OFF Inner Plexiform Layer Of The Rabbit Retina

    This paper in the Journal of Comparative Neurology by  J. Scott Lauritzen, James R. Anderson, Bryan W. Jones, Carl B. Watt, Shoeb Mohammed, John V. Hoang and Robert E. Marc is another effort out of the Marc Laboratory For Connectomics that continues to define complete neural circuits to completeness. This paper is another elucidation of data from the first Rabbit Retinal Connectome volume (RC1) that reveals […]

    Jan 30, 2013 — Read more 1 Comment
  14. Happy Holidays 2012 And A Happy New Year In 2013

    We at Webvision would like to wish you all a very happy holiday season and a happy New Year in 2013.  Continuing on the theme from last years holiday season wishes, we have for you a colorful holiday image titled “Connectomics, First Light” from Robert E. Marc utilizing data generated by Scott Lauritzen, Crystal Sigulinsky […]

    Dec 21, 2012 — Read more No Comments
  15. Connectomics Analysis of Rod-Cone Interaction Networks

    This poster and presentation was presented today at the Federation of American Societies For Experimental Biology (FASEB) meeting in Steamboat Springs, Colorado by J. Scott Lauritzen, James R. Anderson, Carl B. Watt, Bryan W. Jones and Robert E. Marc.  A large size pdf of the poster can be downloaded here.

    Jul 31, 2012 — Read more No Comments
  16. The Synaptic Basis of Rod-Cone Pathway Interactions

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Ft. Lauderdale, Florida by Robert E. Marc, J. Scott Lauritzen, Bryan W. Jones, Carl B. Watt and James R. Anderson.

    May 10, 2012 — Read more No Comments
  17. Diffusely-Stratified OFF Cone Bipolar Cell Inputs to Amacrine Cells in the ON Inner Plexiform Layer

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Ft. Lauderdale, Florida by J. Scott Lauritzen, Bryan W. Jones, Carl B. Watt, Shoeb Mohammed, James R. Anderson, Robert E. Marc.

    May 8, 2012 — Read more No Comments
  18. Retinal Metabolic Response to Cigarette Smoke

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Ft. Lauderdale, Florida by Alexandra D. Butler, William D. Ferrell, Alex Woodell, Carl Atkinson, Bärbel Rohrer, Robert E. Marc and Bryan W. Jones. 

    May 8, 2012 — Read more No Comments
  19. Histologic Correlation of OCT With Diseased Retina In Humans

    This poster was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Ft. Lauderdale, Florida by W. Drew Ferrell, Lloyd Williams, Carl B. Watt, James R. Anderson, Robert E. Marc and Bryan William Jones.  Full size (almost) poster can be seen here.

    May 6, 2012 — Read more No Comments
  20. Rapid Glutamate Receptor 2 Trafficking During Retinal Degeneration

    Yanhua Lin, Bryan W. Jones, Aihua Liu, Félix R. Vazquéz-Chona, J. Scott Lauritzen, W. Drew Ferrell and Robert E. Marc published a paper on rapid changes in glutamate receptor 2 trafficking during retinal degeneration.

    May 1, 2012 — Read more No Comments
  21. Dysmorphic Photoreceptors in a P23H Mutant Rhodopsin Model of Retinitis Pigmentosa Are Metabolically Active and Capable of Regenerating to Reverse Retinal Degeneration

    This paper (and the cover article) is the result of a collaborative effort between Damian C. Lee, Felix R. Vazquez-Chona, W. Drew Ferrell, Beatrice M. Tam, Bryan W. Jones, Robert E. Marc, and Orson L. Moritz.

    Feb 29, 2012 — Read more No Comments
  22. Generation of An Inbred Miniature Pig Model of Retinitis Pigmentosa

    A recent paper by Jason W. Ross, Juan P. Fernandez de Castro, Jianguo Zhao, Melissa Samuel, Eric Walters, Cecilia Rios, Patricia Bray-Ward, Bryan W. Jones, Robert E. Marc, Wei Wang, Liang Zhou, Jennifer M. Noel, Maureen A. McCall, Paul J. DeMarco, Randall S. Prather and Henry J. Kaplan describes the creation of a new model of retinal degenerative disease, specifically autosomal dominant retinitis pigmentosa in a miniature pig model, […]

    Feb 7, 2012 — Read more No Comments
  23. Merry Christmas and Happy New Year, 2011

    Merry Christmas and Happy New Year to you from all of us at Webvision.  This image, a Christmas wreath created by Robert E. Marc is composed of 104 rod bipolar cell axonal fields from the world’s first complete connectome with synaptic level resolution.  Each bipolar cell in this field has been annotated from ultrastructural data […]

    Dec 24, 2011 — Read more 1 Comment
  24. Metabolic Profiling of Activated Retinal Glia

    Presented at the Society for Neuroscience meetings in Washington, D.C. by Felix Vazquez-Chona, William Drew Ferrell, Ed Levine, Bryan William Jones and Robert E. Marc.  Full size poster can be seen here.

    Nov 18, 2011 — Read more No Comments
  25. Proliferative reactive gliosis is compatible with glial metabolic support and neuronal function

    This paper by Vazquez-Chona FR, Swan A, Ferrell WD, Jiang L, Baehr W, Chien WM, Fero M, Marc RE and Levine EM addresses a long standing issue in the field of neuroscience: is the reactive phenotype of glial cells in and of itself detrimental to neural survival or function?

    Oct 17, 2011 — Read more No Comments