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  1. Retinal Metabolic Response to Cigarette Smoke

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Seattle, Washington by Alexandra D. Butler, William D. Ferrell, Alex Woodell, Carl Atkinson, Baerbel Rohrer, Robert E. Marc and Bryan W. Jones. 

    May 7, 2013 — Read more No Comments

  2. Constructive Retinal Plasticity After Selective Ablation of the Photoreceptors

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Seattle, Washington by Corinne N. Beier, myself, Philip Huie, Yannis M. Paulus, Daniel Lavinsky, Loh-Shan B. Leung, Hiroyuki Nomoto,  Robert E. Marc, Daniel V. Palanker, and Alexander Sher.

    May 7, 2013 — Read more No Comments

  3. Sparse Network Principles of GABAergic Amacrine Cell Heterocellular Coupling

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Seattle, Washington by Crystal L. Sigulinsky, J. Scott Lauritzen, John V. Hoang, Carl B. Watt, Bryan W. Jones, James R. Anderson, Shoeb Mohammed and Robert E. Marc.

    May 6, 2013 — Read more No Comments

  4. Tiered Cross-Class Bipolar Cell Gap Junctional Coupling in the Rabbit Retina

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Seattle, Washington by J. Scott Lauritzen, John V. Hoang, Crystal Sigulinsky, Bryan W. Jones, James R. Anderson, Carl B. Watt, Shoeb Mohammed and Robert E. Marc.

    May 6, 2013 — Read more No Comments

  5. Pure Feedforward Amacrine Cells

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Seattle, Washington by Robert E. Marc, Felix R. Vazquez-Chona, John V. Hoang, Crystal Sigulinsky, Carl B. Watt, Bryan W. Jones, James R. Anderson and J. Scott Lauritzen. 

    May 6, 2013 — Read more No Comments

  6. Retinal Remodeling in a Rat Model of the Smith-Lemli-Opitz Syndrome (SLOS)

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Seattle, Washington by Steven J. Fliesler, Christopher C. Goulah, W. Drew Ferrell, Robert E. Marc and Bryan W. Jones.

    May 5, 2013 — Read more No Comments

  7. Building Retinal Connectomes

    There has been quite a bit of discussion of connectomes in the last while with President Obama’s new BRAIN initiative.  It is important to consider some of the requirements of obtaining a true synapse level wiring map in the brain as many are articulating from this initiative.  While there are new technologies that will be [...]

    Apr 22, 2013 — Read more No Comments

  8. Notable Paper: On Cone Bipolar Cell Axonal Synapses In The OFF Inner Plexiform Layer Of The Rabbit Retina

    This paper in the Journal of Comparative Neurology by  J. Scott Lauritzen, James R. Anderson, Bryan W. Jones, Carl B. Watt, Shoeb Mohammed, John V. Hoang and Robert E. Marc is another effort out of the Marc Laboratory For Connectomics that continues to define complete neural circuits to completeness. This paper is another elucidation of data from the first Rabbit Retinal Connectome volume (RC1) that reveals [...]

    Jan 30, 2013 — Read more 1 Comment

  9. Happy Holidays 2012 And A Happy New Year In 2013

    We at Webvision would like to wish you all a very happy holiday season and a happy New Year in 2013.  Continuing on the theme from last years holiday season wishes, we have for you a colorful holiday image titled “Connectomics, First Light” from Robert E. Marc utilizing data generated by Scott Lauritzen, Crystal Sigulinsky [...]

    Dec 21, 2012 — Read more No Comments

  10. Connectomics Analysis of Rod-Cone Interaction Networks

    This poster and presentation was presented today at the Federation of American Societies For Experimental Biology (FASEB) meeting in Steamboat Springs, Colorado by J. Scott Lauritzen, James R. Anderson, Carl B. Watt, Bryan W. Jones and Robert E. Marc.  A large size pdf of the poster can be downloaded here.

    Jul 31, 2012 — Read more No Comments

  11. The Synaptic Basis of Rod-Cone Pathway Interactions

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Ft. Lauderdale, Florida by Robert E. Marc, J. Scott Lauritzen, Bryan W. Jones, Carl B. Watt and James R. Anderson.

    May 10, 2012 — Read more No Comments

  12. Diffusely-Stratified OFF Cone Bipolar Cell Inputs to Amacrine Cells in the ON Inner Plexiform Layer

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Ft. Lauderdale, Florida by J. Scott Lauritzen, Bryan W. Jones, Carl B. Watt, Shoeb Mohammed, James R. Anderson, Robert E. Marc.

    May 8, 2012 — Read more No Comments

  13. Retinal Metabolic Response to Cigarette Smoke

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Ft. Lauderdale, Florida by Alexandra D. Butler, William D. Ferrell, Alex Woodell, Carl Atkinson, Bärbel Rohrer, Robert E. Marc and Bryan W. Jones. 

    May 8, 2012 — Read more No Comments

  14. Histologic Correlation of OCT With Diseased Retina In Humans

    This poster was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Ft. Lauderdale, Florida by W. Drew Ferrell, Lloyd Williams, Carl B. Watt, James R. Anderson, Robert E. Marc and Bryan William Jones.  Full size (almost) poster can be seen here.

    May 6, 2012 — Read more No Comments

  15. Rapid Glutamate Receptor 2 Trafficking During Retinal Degeneration

    Yanhua Lin, Bryan W. Jones, Aihua Liu, Félix R. Vazquéz-Chona, J. Scott Lauritzen, W. Drew Ferrell and Robert E. Marc published a paper on rapid changes in glutamate receptor 2 trafficking during retinal degeneration.

    May 1, 2012 — Read more No Comments

  16. Dysmorphic Photoreceptors in a P23H Mutant Rhodopsin Model of Retinitis Pigmentosa Are Metabolically Active and Capable of Regenerating to Reverse Retinal Degeneration

    This paper (and the cover article) is the result of a collaborative effort between Damian C. Lee, Felix R. Vazquez-Chona, W. Drew Ferrell, Beatrice M. Tam, Bryan W. Jones, Robert E. Marc, and Orson L. Moritz.

    Feb 29, 2012 — Read more 2 Comments

  17. Generation of An Inbred Miniature Pig Model of Retinitis Pigmentosa

    A recent paper by Jason W. Ross, Juan P. Fernandez de Castro, Jianguo Zhao, Melissa Samuel, Eric Walters, Cecilia Rios, Patricia Bray-Ward, Bryan W. Jones, Robert E. Marc, Wei Wang, Liang Zhou, Jennifer M. Noel, Maureen A. McCall, Paul J. DeMarco, Randall S. Prather and Henry J. Kaplan describes the creation of a new model of retinal degenerative disease, specifically autosomal dominant retinitis pigmentosa in a miniature pig model, [...]

    Feb 7, 2012 — Read more No Comments

  18. Merry Christmas and Happy New Year, 2011

    Merry Christmas and Happy New Year to you from all of us at Webvision.  This image, a Christmas wreath created by Robert E. Marc is composed of 104 rod bipolar cell axonal fields from the world’s first complete connectome with synaptic level resolution.  Each bipolar cell in this field has been annotated from ultrastructural data [...]

    Dec 24, 2011 — Read more 1 Comment

  19. Metabolic Profiling of Activated Retinal Glia

    Presented at the Society for Neuroscience meetings in Washington, D.C. by Felix Vazquez-Chona, William Drew Ferrell, Ed Levine, Bryan William Jones and Robert E. Marc.  Full size poster can be seen here.

    Nov 18, 2011 — Read more No Comments

  20. Proliferative reactive gliosis is compatible with glial metabolic support and neuronal function

    This paper by Vazquez-Chona FR, Swan A, Ferrell WD, Jiang L, Baehr W, Chien WM, Fero M, Marc RE and Levine EM addresses a long standing issue in the field of neuroscience: is the reactive phenotype of glial cells in and of itself detrimental to neural survival or function?

    Oct 17, 2011 — Read more No Comments

  21. Retinoid Receptors Trigger Neuritogenesis in Retinal Degenerations

    This paper by Y Lin, BW Jones, A Liu, JF Tucker, K Rapp, L Luo, W Baehr, PS Bernstein, CB Watt, JH Yang, MV Shaw and RE Marc examines the neuronal sprouting or neuritogenesis components of retinal remodeling found in retinal degenerative disease and describes a control process for retinoid X receptors (RXRs) in neuritogenesis. 

    Oct 11, 2011 — Read more 1 Comment

  22. A Photographers Visit to the Moran Eye Center

    A friend of Webvision, renaissance man and photographer extraordinaire, Duncan Davidson visited us at the Moran Eye Center and hung out for a day of science while we performed experiments.  Duncan documented some of the work we did that day in the lovely video he posted to Vimeo above.  You have quite possibly seen Duncan’s [...]

    Jun 25, 2011 — Read more No Comments

  23. ARVO 2011 Snap Shots

    ARVO 2011 has come and gone.  Its taken me a couple of weeks to get through the post ARVO chaos and get caught up on my own work before posting some of the snapshots, but here they are.  If you’d like to post your snapshots from ARVO here, send me an email (webvision@hsc.utah.edu) and we’ll [...]

    May 24, 2011 — Read more 3 Comments

  24. Bipolar Cell “Accessory ON” Input to Amacrine Cells in the OFF Inner Plexiform Layer

    May 4, 2011 — Read more No Comments

  25. Visual Restoration And Circuitry-Retinal Sheet Transplants To Rats With Retinal Degeneration

    May 4, 2011 — Read more No Comments