Happy Holidays from Webvision. We wish you a happy, healthy and productive holiday season and New Year.
Gabe Luna from Steve Fisher and Geoff Lewis’s retinal cell biology group at UC Santa Barbara Neuroscience Research Institute provided this festive laser confocal image of a wholemount from a normal retina with dye-filled retinal astrocytes using Lucifer Yellow (green) and Alexa Fluor 568 (red) which were used to examine the spatial organization between individual astrocytes.
One of the common questions people have is what it means to be colorblind since that is one of the common visual deficit manifestations that they can relate to. Color blindness (pretty good article on Wikipedia there) is very common and just about everyone knows someone who does not see the world quite like they do because of a form of color blindness.
I have a post over on Jonesblog that renders some natural scenes as protanopes, deuteranopes and tritanopes would see them and talks about how to simulate your own images for various forms of color blindness.
We have another beautiful image (larger size image here) from Gabe Luna in Steve Fisher’s and Geoff Lewis‘ group. This image representing the evolution of disease post retinal detachment, earned Honorable Mention in the 2013 Olympus Bioscapes International Digital Imaging Competition.
The image is a 60x image using laser scanning confocal image of the murine retinal nerve fiber layer after 2 weeks after retinal detachment. The ganglion cell axons (red), astrocytes (green), and blood vessels (blue) are labeled using SMI-32, GFAP, and Collagen IV antibodies respectively.
We had a recent case of Polypoidal Choroidal Vasculopathy here at the Moran Eye Center, imaged here as an ICG angiogram (large image here). Polypoidal Choroidal Vasculopathy is an uncommon disorder of the choroidal circulation summarized in the Ciardella et. al. paper Polypoidal Choroidal Vasculopathy.
“The primary abnormality involves the choroidal circulation, and the characteristic lesion is an inner choroidal vascular network of vessels ending in an aneurysmal bulge or outward projection, visible clinically as a reddish orange, spheroid, polyp-like structure…. The natural course of the disease often follows a remitting-relapsing course, and clinically, it is associated with chronic, multiple, recurrent serosanguineous detachments of the retinal pigment epithelium and neurosensory retina with long-term preservation of good vision.”
ICG angiogram provided by James Gilman of the Moran Eye Center.