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  1. TRPV4 Regulates Calcium Homeostasis, Cytoskeletal Remodeling, Conventional Outflow and Intraocular Pressure

    Glaucoma is the main cause of irreversible blindness in the world. In most common types of the disease, the optic nerve is damaged by an increase in intraocular pressure (IOP) which blocks fluid drainage through canals in the eye. There is currently no cure, however, the disease can be treated by lowering IOP. Unfortunately, all IOP-lowering drugs that in the market today target the […]

    Aug 17, 2016 — Read more No Comments
  2. Store-Operated Calcium Entry In Müller Glia Is Controlled By Synergistic Activation Of TRPC And Orai Channels

    There is a new publication out in the Journal of Neuroscience (cover story) from Moran Eye Center scientists, Store-Operated Calcium Entry In Müller Glia Is Controlled By Synergistic Activation Of TRPC And Orai Channels authored by Tünde Molnár, Oleg Yarishkin, Peter Barabas, Anthony Iuso, Bryan William Jones, Robert Marc, Tam Phuong, and David Krizaj.

    Mar 18, 2016 — Read more No Comments
  3. Upcoming VIG Seminar: June 18th @ NOON

      There is an upcoming Vision Interest Group featuring Sarah Anderson from the Vetter Lab and Amanda Leung from the Levine Lab.  Will be held on June 18th at noon in the west John A. Moran Eye Center Auditorium.

    Jun 8, 2015 — Read more No Comments
  4. Müller Cell Metabolic Chaos During Degeneration

    This abstract was presented today at the 2015 Association for Research in Vision and Opthalmology (ARVO) meetings in Denver, Colorado by  Rebecca L. Pfeiffer, Bryan W. Jones and Robert E. Marc. Purpose: Müller cells (MCs) play a critical role in glutamate (E) metabolism and carbon skeleton cycling in retina. MCs demonstrate changes in metabolism and morphology during retinal degeneration. The timing, […]

    May 7, 2015 — Read more No Comments
  5. Upcoming VIG: February 19th @NOON Moran Auditorium west

    There is an upcoming Vision Interest Group featuring Felix Vazquez-Chona from the Marc and Levine Labs and Brent Young from the Tian Lab.  Will be held on February 19th at noon in the west John A. Moran Eye Center Auditorium.

    Feb 10, 2015 — Read more No Comments
  6. Upcoming VIG January 15th @ Noon

    There is an upcoming Vision Interest Group featuring Nduka Enemchukwu from the Fu Lab and Aruna Goruspudi from the Bernstein Lab.  Will be held on November 20th at noon in the west John A. Moran Eye Center Auditorium.

    Jan 9, 2015 — Read more No Comments
  7. Upcoming VIG seminar: November 20th @ NOON

    There is an upcoming Vision Interest Group featuring Kevin Breen from the Vetter lab and Crystal Sigulinsky from the Marc Lab.  Will be held on November 20th at noon in the west John A. Moran Eye Center Auditorium.

    Nov 10, 2014 — Read more No Comments
  8. Upcoming VIG: October 16th @ Noon, Moran Auditorium West

    There is an upcoming Vision Interest Group featuring Kyle Jenks from the Jason Shepherd lab and Kevin Huang from the Ning Tian Lab.  Will be held on October 16th at noon in the west John A. Moran Eye Center Auditorium.

    Oct 2, 2014 — Read more No Comments
  9. New Webvision Chapter on Albinism by Don Creel

    We have a new chapter on Albinism in Webvision by Don Creel who describes the clinical picture of albinism along with some of the anatomy and electrophysiology of the visual and auditory systems.  

    Sep 6, 2014 — Read more No Comments
  10. Moran Eye Center Researcher Robert E. Marc: 2014 Paul Kayser Award In Retina Research

    Our colleague and Director of Research at the University of Utah‘s Moran Eye Center, Robert E. Marc, Ph.D. has been named by the International Society for Eye Research as a recipient of the Paul Kayser International Award in Retina Research.  The award will be presented to Dr. Marc during the 2014 ISER Biennial Meeting of […]

    Jun 25, 2014 — Read more No Comments
  11. Thy-1 Expressed In CNV And Increased In migrating Choroidal ECs In Human Neovascular AMD

    This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by Haibo Wang, Yanchao Jiang and M. Elizabeth Hartnett. Thy-1 regulates VEGF-induced choroidal endothelial cell migration  Dept of Ophthalmology, John A. Moran Eye Center, The University of Utah-Salt Lake City.  Purpose: Choroidal endothelial cell (CEC) activation and migration […]

    May 8, 2014 — Read more No Comments
  12. Müller Cell-derived VEGF164 Knockdown Reduces Retinal Neovascularization In A Rat Model Of Retinopathy Of Prematurity

      This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by  Deeksha Gambhir, Yanchao Jiang, George W. Smith, Zhihong Yang, Haibo Wang, Lori Fotheringham and M. Elizabeth Hartnett. Full size poster available here.

    May 7, 2014 — Read more No Comments
  13. A Study of PDZ Domain-Containing 7 (PDZD7) in the Mouse Retina

    This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by  Junhuang Zou, Tihua Zheng and Jun Yang. Full size poster can be downloaded here. Purpose: PDZD7 is a newly identified modifier and contributor gene of Usher syndrome (USH). In the inner ear, PDZD7 colocalizes with GPR98, […]

    May 7, 2014 — Read more No Comments
  14. A Synaptic Basis for Small World Network Design in the ON Inner Plexiform Layer of the Rabbit Retina

    This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by J Scott Lauritzen, Noah T. Nelson, Crystal L. Sigulinsky, Nathan Sherbotie, John Hoang, Rebecca L. Pfeiffer, James R. Anderson, Carl B. Watt, Bryan W. Jones and Robert E. Marc. Purpose: Converging evidence suggests that large- and intermediate-scale neural networks throughout the nervous system exhibit small world’ […]

    May 6, 2014 — Read more No Comments
  15. The Role of NMDA Receptor Activity in Retinal Ganglion Cell Dendrite Development

      This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by Eerik M. Elias, Ping Wang and Ning Tian. Full size poster available here. Purpose: To elucidate mechanisms underlying the dendrite developmental plasticity of retinal ganglion cells, we examined the role of glutamate receptors on retinal ganglion […]

    May 6, 2014 — Read more No Comments
  16. Suppressing Thyroid Hormone Signaling Preserves Cone Photoreceptors in Mouse Models of Retinal Degeneration

    This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by Xi-Qin Ding, Hongwei Ma, Arjun Thapa, Lynsie Morris, T M. Redmond and Wolfgang Baehr. Full size poster available here. Purpose: Cone phototransduction and survival of cones in the human macula is essential for color vision and for […]

    May 5, 2014 — Read more No Comments
  17. Metabolic Changes Associated With Müller Cells In A Transgenic Rabbit Model Of Retinal Degeneration

    This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by  Rebecca L. Pfeiffer, Bryan W. Jones and Robert E. Marc. Purpose: Müller cells play a central role in retinal metabolism via the glutamate cycle. During retinal degeneration Müller cells are among the first to demonstrate changes, reflected […]

    May 4, 2014 — Read more No Comments
  18. Retinitis Pigmentosa 2 Protein Regulates Transport Of Isoprenylated Proteins To Photoreceptor Outer Segments

    This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by Houbin Zhang, Li Jiang, Christin Hanke and Wolfgang Baehr. Full size poster can be downloaded here. Purpose: X-linked retinitis pigmentosa (XLRP) is a devastating form of retinal degeneration, manifesting early in life with symptoms of night blindness, visual […]

    May 4, 2014 — Read more No Comments
  19. Arl3 Rod-Specific Knockout Displays RP-Like Photoreceptor Degeneration

    This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by Christin Hanke, Houbin Zhang, Cecilia D. Gerstner, Jeanne M. Frederick AND Wolfgang Baehr. Full size poster can be downloaded here. Purpose: Arf-like protein 3 (Arl3) localizes predominantly in the photoreceptor inner segment. Germline Arl3 knockout mice do not […]

    May 4, 2014 — Read more No Comments
  20. Notable paper: Lhx2 Balances Progenitor Maintenance With Neurogenic Output And Promotes Competence State Progression In The Developing Retina

    The Levine lab here at the Moran Eye Center has a new publication out in the Journal of Neuroscience and even scored the cover.  Specifically, the manuscript was authored by Patrick J. Gordon, Sanghee Yun, Anna M. Clark, Edwin S. Monuki, L. Charles Murtaugh, and Edward M. Levine.  The Levine team explored how multipotent retinal progenitor cells […]

    Jul 29, 2013 — Read more No Comments
  21. Doctoral Dissertation Defense: Nikko Ronquillo

    Nikko Ronquillo will be defending his dissertation on Wednesday, May 15th at 2:00pm in the Moran Eye Center auditorium on the 1st floor.  Nikko’s dissertation, performed in Wolfgang Baehr’s laboratory is on the Functional and morphological studies of the NPHP5 mouse model: insights into Senior-Løken Syndrome.    

    May 14, 2013 — Read more 1 Comment
  22. The Combined Effect With Erythropoietin And VEGF In Retinal Angiogenesis

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Seattle, Washington by  Zhihong Yang, Haibo Wang, Yanchao Jiang, Manabu Mccloskey and ME Hartnett.

    May 9, 2013 — Read more No Comments
  23. Retinal Metabolic Response to Cigarette Smoke

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Seattle, Washington by Alexandra D. Butler, William D. Ferrell, Alex Woodell, Carl Atkinson, Baerbel Rohrer, Robert E. Marc and Bryan W. Jones. 

    May 7, 2013 — Read more No Comments
  24. Whole Exome Sequencing (WES) Identifies a Mutation in ALPK1 Responsible for a Novel, Autosomal Dominant Disorder of Vision Loss, Splenomegaly, and Pancytopenia

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Seattle, Washington by Lloyd B. Williams, Chad D. Huff, Denise Morgan, Rosann Robinson, Margaux Morrison, Krista Kinard, George Rodgers, Kathleen B. Digre, Kathleen and Margaret DeAngelis.

    May 7, 2013 — Read more No Comments
  25. MRI of the Capsular Bag in Pseudophakic Human Donor Eyes

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Seattle, Washington by Lawrence Strenk, Susan Strenk, Liliana Werner, Nick Mamalis.

    May 7, 2013 — Read more No Comments