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  1. TRPV4 Regulates Calcium Homeostasis, Cytoskeletal Remodeling, Conventional Outflow and Intraocular Pressure

    Glaucoma is the main cause of irreversible blindness in the world. In most common types of the disease, the optic nerve is damaged by an increase in intraocular pressure (IOP) which blocks fluid drainage through canals in the eye. There is currently no cure, however, the disease can be treated by lowering IOP. Unfortunately, all IOP-lowering drugs that in the market today target the […]

    Aug 17, 2016 — Read more No Comments
  2. Seminar: Linking Metabolism, Vascular Maintenance, and Photoreceptor Homeostasis in the Retina

    Peter Westenskow, Research Associate, Department of Cell and Molecular Biology, The Scripps Research Institute Staff Scientist, Lowy Medical Research Institute will be delivering a seminar on Linking Metabolism, Vascular Maintenance, and Photoreceptor Homeostasis in the Retina on Wednesday, July 2nd 15th at Noon  in the the Moran Eye Center auditorium. Abstract: Functional interactions between neurons, vasculature, and glia within neurovascular units […]

    Jul 2, 2015 — Read more No Comments
  3. Seminar: Fat3 – An Unusual Cadherin Regulating Retinal Lamination and Stratification

    Michael Deans, Assistant Professor and Director of Research, Otolaryngology, University of Utah will be delivering a seminar on Fat3 – An Unusual Cadherin Regulating Retinal Lamination and Stratification on Thursday, July 2nd 24th at Noon  in the the Moran Eye Center auditorium. Abstract: Neurons receive signals through dendrites that vary widely in number and organization, ranging from one primary dendrite to multiple […]

    Jul 2, 2015 — Read more No Comments
  4. Seminar: Cellular and Molecular Mechanisms of Optic Cup Morphogenesis

      Kristen Kwan, Assistant Professor of Human Genetics, University of Utah will be delivering a seminar on Cellular and Molecular Mechanisms of Optic Cup Morphogenesis on Wednesday, June 24th at Noon  in the the Moran Eye Center auditorium. Abstract: Developmental defects in eye structure can cause visual impairment in newborns.  These defects often arise very early in eye development, when the basic […]

    Jun 10, 2015 — Read more No Comments
  5. Upcoming VIG Seminar: June 18th @ NOON

      There is an upcoming Vision Interest Group featuring Sarah Anderson from the Vetter Lab and Amanda Leung from the Levine Lab.  Will be held on June 18th at noon in the west John A. Moran Eye Center Auditorium.

    Jun 8, 2015 — Read more No Comments
  6. Progression of Geographic Atrophy

    These retinal images are from an 84 year old white male who presented to the Moran Eye Center in 2008.  He was diagnosed and followed for dry age-related macular degeneration (AMD) with serial autofluorescent photographs showing progression of geographic atrophy of the RPE from 2008 to 2014. These images were prepared by James Gilman of the Moran Eye Center.   […]

    May 28, 2015 — Read more No Comments
  7. Müller Cell Metabolic Chaos During Degeneration

    This abstract was presented today at the 2015 Association for Research in Vision and Opthalmology (ARVO) meetings in Denver, Colorado by  Rebecca L. Pfeiffer, Bryan W. Jones and Robert E. Marc. Purpose: Müller cells (MCs) play a critical role in glutamate (E) metabolism and carbon skeleton cycling in retina. MCs demonstrate changes in metabolism and morphology during retinal degeneration. The timing, […]

    May 7, 2015 — Read more No Comments
  8. Upcoming VIG: February 19th @NOON Moran Auditorium west

    There is an upcoming Vision Interest Group featuring Felix Vazquez-Chona from the Marc and Levine Labs and Brent Young from the Tian Lab.  Will be held on February 19th at noon in the west John A. Moran Eye Center Auditorium.

    Feb 10, 2015 — Read more No Comments
  9. Seminar: How Inhibiting The Dimerization Of Vitamin A and/or Catalyzing The Reduction of Quinones May Prevent Retinal Degeneration

    Ilyas Washington from Columbia University Medical Center will be delivering a seminar on How Inhibiting The Dimerization Of Vitamin A and/or Catalyzing The Reduction of Quinones May Prevent Retinal Degeneration on Wednesday, February 11th, 2015 in the Moran Eye Center auditorium. Abstract:  Many human conditions, originating from multiple genetic and environmental pressures, converge to overproduce superoxide radical anions. The […]

    Feb 2, 2015 — Read more No Comments
  10. Upcoming VIG January 15th @ Noon

    There is an upcoming Vision Interest Group featuring Nduka Enemchukwu from the Fu Lab and Aruna Goruspudi from the Bernstein Lab.  Will be held on November 20th at noon in the west John A. Moran Eye Center Auditorium.

    Jan 9, 2015 — Read more No Comments
  11. Moran Eye Center Sets Up Eye Camp In Guatemala

    The Moran Eye Center travels globally as one of their missions for International Outreach and provides eye care in remote places around the world that are medically underserved from an ophthalmology perspective. This is a short video showing the Moran Eye Center setting up an eyecamp in Salma, Guatemala on Dec. 9th. This includes moving […]

    Dec 11, 2014 — Read more No Comments
  12. Upcoming VIG seminar: November 20th @ NOON

    There is an upcoming Vision Interest Group featuring Kevin Breen from the Vetter lab and Crystal Sigulinsky from the Marc Lab.  Will be held on November 20th at noon in the west John A. Moran Eye Center Auditorium.

    Nov 10, 2014 — Read more No Comments
  13. Call For Proposals, Vision Art Exhibit

    The Moran Eye Center is issuing a call for proposals for two different art exhibits related to vision that we are curating: a permanent collection which will be housed in the new Mid-Valley Health Center and an exhibit that will be held at Art Access Gallery from April 17 – May 8th, 2015. The deadline for […]

    Nov 2, 2014 — Read more No Comments
  14. Upcoming VIG: October 16th @ Noon, Moran Auditorium West

    There is an upcoming Vision Interest Group featuring Kyle Jenks from the Jason Shepherd lab and Kevin Huang from the Ning Tian Lab.  Will be held on October 16th at noon in the west John A. Moran Eye Center Auditorium.

    Oct 2, 2014 — Read more No Comments
  15. Seminar: Circadian Dysfunction In The Pathogenesis Of Diabetic Retinopathy

    Maria Grant, Professor and Marilyn K. Glick Senior Chair, from the Eugene and Marilyn Glick Eye Institute, Department of Ophthalmology and Department of Cellular and Integrative Physiology, Indiana University School of Medicine will be delivering a seminar in the Moran Eye Center auditorium on “A Broken Clock: Circadian Dysfunction In The Pathogenesis Of Diabetic Retinopathy” on Wednesday, October 1st […]

    Sep 20, 2014 — Read more No Comments
  16. Upcoming VIG: September 18th @ NOON

    There is an upcoming Vision Interest Group featuring Hui Xu from the Yingbin Fu lab and Rebecca Pfeiffer from the Marc Lab.  Will be held on September 18th at noon in the west John A. Moran Eye Center Auditorium.

    Sep 10, 2014 — Read more No Comments
  17. Moran Eye Center Researcher Robert E. Marc: 2014 Paul Kayser Award In Retina Research

    Our colleague and Director of Research at the University of Utah‘s Moran Eye Center, Robert E. Marc, Ph.D. has been named by the International Society for Eye Research as a recipient of the Paul Kayser International Award in Retina Research.  The award will be presented to Dr. Marc during the 2014 ISER Biennial Meeting of […]

    Jun 25, 2014 — Read more No Comments
  18. Thy-1 Expressed In CNV And Increased In migrating Choroidal ECs In Human Neovascular AMD

    This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by Haibo Wang, Yanchao Jiang and M. Elizabeth Hartnett. Thy-1 regulates VEGF-induced choroidal endothelial cell migration  Dept of Ophthalmology, John A. Moran Eye Center, The University of Utah-Salt Lake City.  Purpose: Choroidal endothelial cell (CEC) activation and migration […]

    May 8, 2014 — Read more No Comments
  19. Müller Cell-derived VEGF164 Knockdown Reduces Retinal Neovascularization In A Rat Model Of Retinopathy Of Prematurity

      This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by  Deeksha Gambhir, Yanchao Jiang, George W. Smith, Zhihong Yang, Haibo Wang, Lori Fotheringham and M. Elizabeth Hartnett. Full size poster available here.

    May 7, 2014 — Read more No Comments
  20. A Study of PDZ Domain-Containing 7 (PDZD7) in the Mouse Retina

    This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by  Junhuang Zou, Tihua Zheng and Jun Yang. Full size poster can be downloaded here. Purpose: PDZD7 is a newly identified modifier and contributor gene of Usher syndrome (USH). In the inner ear, PDZD7 colocalizes with GPR98, […]

    May 7, 2014 — Read more No Comments
  21. A Synaptic Basis for Small World Network Design in the ON Inner Plexiform Layer of the Rabbit Retina

    This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by J Scott Lauritzen, Noah T. Nelson, Crystal L. Sigulinsky, Nathan Sherbotie, John Hoang, Rebecca L. Pfeiffer, James R. Anderson, Carl B. Watt, Bryan W. Jones and Robert E. Marc. Purpose: Converging evidence suggests that large- and intermediate-scale neural networks throughout the nervous system exhibit small world’ […]

    May 6, 2014 — Read more No Comments
  22. The Role of NMDA Receptor Activity in Retinal Ganglion Cell Dendrite Development

      This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by Eerik M. Elias, Ping Wang and Ning Tian. Full size poster available here. Purpose: To elucidate mechanisms underlying the dendrite developmental plasticity of retinal ganglion cells, we examined the role of glutamate receptors on retinal ganglion […]

    May 6, 2014 — Read more No Comments
  23. Suppressing Thyroid Hormone Signaling Preserves Cone Photoreceptors in Mouse Models of Retinal Degeneration

    This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by Xi-Qin Ding, Hongwei Ma, Arjun Thapa, Lynsie Morris, T M. Redmond and Wolfgang Baehr. Full size poster available here. Purpose: Cone phototransduction and survival of cones in the human macula is essential for color vision and for […]

    May 5, 2014 — Read more No Comments
  24. Metabolic Changes Associated With Müller Cells In A Transgenic Rabbit Model Of Retinal Degeneration

    This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by  Rebecca L. Pfeiffer, Bryan W. Jones and Robert E. Marc. Purpose: Müller cells play a central role in retinal metabolism via the glutamate cycle. During retinal degeneration Müller cells are among the first to demonstrate changes, reflected […]

    May 4, 2014 — Read more No Comments
  25. Retinitis Pigmentosa 2 Protein Regulates Transport Of Isoprenylated Proteins To Photoreceptor Outer Segments

    This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by Houbin Zhang, Li Jiang, Christin Hanke and Wolfgang Baehr. Full size poster can be downloaded here. Purpose: X-linked retinitis pigmentosa (XLRP) is a devastating form of retinal degeneration, manifesting early in life with symptoms of night blindness, visual […]

    May 4, 2014 — Read more No Comments