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  1. Interesting: The Spatial Organization Of Cholinergic Mosaics In The Adult Mouse Retina

    This Short Communication published in the European Journal of Neuroscience back in 2000 by Lucia Galli-Resta, Elena Novelli, Maila Volpini and Enrica Strettoi was a paper I did not know existed.  That said, I ran into it the other day looking for some reference material and found it to be quite useful.  This communication represents an analysis of […]

    Feb 13, 2013 — Read more No Comments
  2. Undersized Dendritic Arborizations in Retinal Ganglion Cells of the rd1 Mutant Mouse: A Paradigm of Early Onset Photoreceptor Degeneration

    This paper by Devid Damiani, Elena Novelli, Francesca Mazzoni and Enrica Strettoi documents continued negative plasticity in retina by examining ganglion cells in the rd1 mouse.  The rd1 mouse is one of many models of retinal degenerative disease, in this case as an autosomal recessive retinal degenerative disease.  This work gets at the remodeling issue […]

    Aug 8, 2012 — Read more No Comments
  3. Age-Related Changes In The Daily Rhythm of Photoreceptor Functioning And Circuitry In A Melatonin-Proficient Mouse Strain

    This is an interesting study in PLoS One examining the involvement of melatonin in the retina, particularly in the survival of retinal neurons through aging studies in CH3-f+/+ mice, a melatonin proficient mouse strain.  As expected, certain physiological measures (a and b waves) are lost during aging, and in particular, the daily circadian rhythms of those measures. […]

    Jun 5, 2012 — Read more No Comments
  4. Notable Paper: Localization of Melatonin Receptor 1 in Mouse Retina and Its Role in the Circadian Regulation of the Electroretinogram and Dopamine Levels

    I’ve watched the development of the circadian rhythm research starting with Joe Takahashi‘s work discovering CLOCK in the mammalian SCN back in 1994.  Since then there has been an explosion of circadian rhythm biology work including an I suppose, unsurprising amount of research in the retina proper. This paper by Anamika Sengupta, Kenkichi Baba, Francesca Mazzoni, Nikita V. Pozdeyev, Enrica […]

    Oct 18, 2011 — Read more No Comments