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  1. Upcoming VIG: September 18th @ NOON

    There is an upcoming Vision Interest Group featuring Hui Xu from the Yingbin Fu lab and Rebecca Pfeiffer from the Marc Lab.  Will be held on September 18th at noon in the west John A. Moran Eye Center Auditorium.

    Sep 10, 2014 — Read more No Comments
  2. Metabolic Changes Associated With Müller Cells In A Transgenic Rabbit Model Of Retinal Degeneration

    This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by  Rebecca L. Pfeiffer, Bryan W. Jones and Robert E. Marc. Purpose: Müller cells play a central role in retinal metabolism via the glutamate cycle. During retinal degeneration Müller cells are among the first to demonstrate changes, reflected […]

    May 4, 2014 — Read more No Comments
  3. Abstract Human Retina

    This image of ganglion cells, Müller cells and starburst amacrine cells in the human retina is from a patient suffering from retinitis pigmentosa (RP).  This disease this patient suffered from slowly causes people affected with this disease to go blind and is a constant reminder to me of why we engage in our research. For some, this is a pretty, […]

    Oct 17, 2013 — Read more No Comments
  4. Interesting Paper: Gene Expression Changes Within Müller Glial Cells in Retinitis Pigmentosa

    Retinal degenerations are accompanied by retinal remodeling events.  These events alter the structure and function of the retina and involve to a large extent, Müller cells which seem to serve as pathways for neuronal migration.  This paper by Karin Roesch, Michael B. Stadler and Constance L. Cepko looks at gene expression changes in the Müller cells, one […]

    Nov 13, 2012 — Read more No Comments
  5. Activated Müller Glia

    Friend of Webvision, Peter Westenskow in the Friedlander Laboratory sent us this beautiful image of activated Müller glia in a stressed mouse eye.  You can see the scar in the photoreceptor layer towards the top of the image.  The mouse line is VLDLR -/-.  These mice exhibit aberrant neovascular tufts that invade the ONL and eventually […]

    Dec 23, 2011 — Read more No Comments
  6. Proliferative reactive gliosis is compatible with glial metabolic support and neuronal function

    This paper by Vazquez-Chona FR, Swan A, Ferrell WD, Jiang L, Baehr W, Chien WM, Fero M, Marc RE and Levine EM addresses a long standing issue in the field of neuroscience: is the reactive phenotype of glial cells in and of itself detrimental to neural survival or function?

    Oct 17, 2011 — Read more No Comments
  7. Targeting Müller Cell-derived VEGF With Short Hairpin RNA

    May 4, 2011 — Read more No Comments
  8. Genetic Dissection of p27-Mediated Reactive Gliosis

    May 3, 2011 — Read more No Comments