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  1. Deep Learning Algorithm for Detection of Diabetic Retinopathy

    A very cool paper was published in JAMA yesterday that is a result of Google Research asking if machine learning and computer vision could improve retinal fundoscopic examinations of patients with diabetic retinopathy.  The outcome of course is increased patient screening for physicians with limited resources.

    Nov 30, 2016 — Read more No Comments
  2. Seminar: Calcium Homeostasis in Mammalian Rod and Cone Photoreceptors

    Vladimir Kefalov, Professor of Ophthalmology and Visual Sciences at Washington University in St. Louis will be delivering a seminar on “Calcium Homeostasis in Mammalian Rod and Cone Photoreceptors” on Wednesday, May 11th at 12:00 Noon in the Moran Eye Center auditorium. Abstract: Calcium plays an important role in the function and health of photoreceptors. Calcium modulates the phototransduction cascade and […]

    Apr 20, 2016 — Read more No Comments
  3. Bruch’s Membrane

    Bruch’s membrane is a highly specialized and multi-laminar structure in our retinas that forms the basis for mediating interactions between the retinal pigment epithelium and blood flow from the choroid.  I’ve not seen many good images online, so figured this image from mouse would be a good addition showing the relationship of the basal surface […]

    Sep 5, 2015 — Read more No Comments
  4. Retinal Astrocytic Hamartoma

    This is a 58 year old white female with a retinal astrocytic hamartoma on her right optic nerve.  Retinal astrocytic hamartomas are glial tumors of the retinal nerve fiber layer arising from retinal astrocytes. This animated GIF file illustrates the height of the hamartoma and is another example of where animated gifs can be a fantastic […]

    May 23, 2015 — Read more No Comments
  5. Happy Holidays, 2014 From Webvision

    We at Webvision would like to wish you the very best this holiday season.  As in past years, we like to post an image from retinal science that is somehow evocative of the Holiday Season and this year, Gabe Luna from the Steve Fisher / Geoff Lewis laboratory delivers a stunning image of astrocytes in a […]

    Dec 23, 2014 — Read more No Comments
  6. Peek Vision, Retinal Exams With Smart Phones

    We talked about using smartphones for ophthalmological examinations before here on Webvision, and we now have a bit more information into the logistics of how the Peek Vision project will be done on this Mashable post with a clip on attachment being developed through funding from an Indiegogo campaign.   There is also a wonderful background video of TED […]

    Dec 2, 2014 — Read more No Comments
  7. Upcoming VIG: September 18th @ NOON

    There is an upcoming Vision Interest Group featuring Hui Xu from the Yingbin Fu lab and Rebecca Pfeiffer from the Marc Lab.  Will be held on September 18th at noon in the west John A. Moran Eye Center Auditorium.

    Sep 10, 2014 — Read more No Comments
  8. New Webvision Chapter on Albinism by Don Creel

    We have a new chapter on Albinism in Webvision by Don Creel who describes the clinical picture of albinism along with some of the anatomy and electrophysiology of the visual and auditory systems.  

    Sep 6, 2014 — Read more No Comments
  9. Seminar: Light Damage

    Jeannie Chen, Professor in the Department of Cell and Neurobiology, the Zikha Neurogenetic Institute, Keck School of Medicine, University of Southern California will present a seminar at noon on Wednesday, September 17th in the Moran Eye Center auditorium on Light Damage. Abstract:  Excessive light exposure is known to harm the retina and exacerbates disease progression […]

    Sep 2, 2014 — Read more No Comments
  10. Moving Jumping Spider Retinas

    We’ve talked about jumping spiders before here on Webvision as they are an amazing animal with very well developed vision.  However, their retinas and visual pathways are very different from the vertebrate retinas in that they use image defocusing for depth perception rather than parallax like humans and other vertebrates do.  Figuring out spider vision has […]

    Jul 13, 2014 — Read more No Comments
  11. Moran Eye Center Researcher Robert E. Marc: 2014 Paul Kayser Award In Retina Research

    Our colleague and Director of Research at the University of Utah‘s Moran Eye Center, Robert E. Marc, Ph.D. has been named by the International Society for Eye Research as a recipient of the Paul Kayser International Award in Retina Research.  The award will be presented to Dr. Marc during the 2014 ISER Biennial Meeting of […]

    Jun 25, 2014 — Read more No Comments
  12. A Synaptic Basis for Small World Network Design in the ON Inner Plexiform Layer of the Rabbit Retina

    This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by J Scott Lauritzen, Noah T. Nelson, Crystal L. Sigulinsky, Nathan Sherbotie, John Hoang, Rebecca L. Pfeiffer, James R. Anderson, Carl B. Watt, Bryan W. Jones and Robert E. Marc. Purpose: Converging evidence suggests that large- and intermediate-scale neural networks throughout the nervous system exhibit small world’ […]

    May 6, 2014 — Read more No Comments
  13. The Role of NMDA Receptor Activity in Retinal Ganglion Cell Dendrite Development

      This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by Eerik M. Elias, Ping Wang and Ning Tian. Full size poster available here. Purpose: To elucidate mechanisms underlying the dendrite developmental plasticity of retinal ganglion cells, we examined the role of glutamate receptors on retinal ganglion […]

    May 6, 2014 — Read more No Comments
  14. Arl3 Rod-Specific Knockout Displays RP-Like Photoreceptor Degeneration

    This abstract was presented today at the 2014 Association for Research in Vision and Opthalmology (ARVO) meetings in Orlando, Florida by Christin Hanke, Houbin Zhang, Cecilia D. Gerstner, Jeanne M. Frederick AND Wolfgang Baehr. Full size poster can be downloaded here. Purpose: Arf-like protein 3 (Arl3) localizes predominantly in the photoreceptor inner segment. Germline Arl3 knockout mice do not […]

    May 4, 2014 — Read more No Comments
  15. Polypoidal Choroidal Vasculopathy

    We had a recent case of Polypoidal Choroidal Vasculopathy here at the Moran Eye Center, imaged here as an ICG angiogram (large image here).  Polypoidal Choroidal Vasculopathy is an uncommon disorder of the choroidal circulation summarized in the Ciardella et. al. paper Polypoidal Choroidal Vasculopathy. “The primary abnormality involves the choroidal circulation, and the characteristic lesion is […]

    Dec 12, 2013 — Read more No Comments
  16. Optic Nerve Head Drusen

    Drusen in the retina is a common finding in aging retina, forming deposits in the retina between Bruch’s membrane and the retinal pigment epithelium.  Most people over 40 start to accumulate some drusen, but increasing amounts of drusen formation can indicate pathological developments associated with age related macular degeneration, (AMD).  Cristine Curcio has been chasing […]

    Nov 1, 2013 — Read more No Comments
  17. Abstract Human Retina

    This image of ganglion cells, Müller cells and starburst amacrine cells in the human retina is from a patient suffering from retinitis pigmentosa (RP).  This disease this patient suffered from slowly causes people affected with this disease to go blind and is a constant reminder to me of why we engage in our research. For some, this is a pretty, […]

    Oct 17, 2013 — Read more No Comments
  18. Seminar: Marla Feller, The Development Of Functional Circuits In The Retina

    The University of Utah Program in Neuroscience presents Dr. Marla Feller who will deliver a seminar in the Eccles Institute of Human Genetics auditorium, Tuesday October 15th, 2013 at 4:00pm.  Dr. Feller will discuss the development of functional circuits in the retina.  

    Oct 10, 2013 — Read more No Comments
  19. Portrait Of Vision Scientist: Stuart Mangel, Ph.D.

    This image of Stuart Mangel was made in Berlin, Germany at the 2012 ISER meeting.  Stuart is Professor in the Department of Neuroscience at Ohio State University.  Stuart came out of John Dowling’s lab at Harvard and has contributed mightily to our understanding of synaptic plasticity, circadian rhythms and retinal circuitry/information processing in the retina. Its […]

    Jun 21, 2013 — Read more No Comments
  20. The Cilium

    With the exception of a few types of cells, (acinar cells, T lymphocytes and hepatocytes), every cell in your body has a cilia.  In the vision community, we are used to seeing these structures in the distal portion of the photoreceptors.  The reality is that every cell in the retina has a cilium and some cells […]

    Jun 7, 2013 — Read more No Comments
  21. GFAP And Collagen IV In Retina

    Friend of Webvision, Gabriel Luna sent this laser confocal image of a wholemount from a normal mouse retina immuno-stained with anti-GFAP (red; astrocytes) and anti-Collagen IV (blue; blood vessels).  Gabe is out of the Steve Fisher and Geoff Lewis’s retinal cell biology group at UC Santa Barbara Neuroscience Research Institute. Thanks Gabe!    

    May 22, 2013 — Read more No Comments
  22. New Webvision Chapter: Evolution of Phototransduction, Vertebrate Photoreceptors and Retina

    After much work by a number of our contributors, not the least of whom is the author of this particular effort, we have a spectacular new addition to Webvision:  A section on the Evolution of Phototransduction, Vertebrate Photoreceptors and Retina by Trevor D. Lamb.  Be sure to check it out and let us know what you […]

    May 15, 2013 — Read more No Comments
  23. Constructive Retinal Plasticity After Selective Ablation of the Photoreceptors

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Seattle, Washington by Corinne N. Beier, Bryan W. Jones, Philip Huie, Yannis M. Paulus, Daniel Lavinsky, Loh-Shan B. Leung, Hiroyuki Nomoto,  Robert E. Marc, Daniel V. Palanker, and Alexander Sher.

    May 7, 2013 — Read more No Comments
  24. Sparse Network Principles of GABAergic Amacrine Cell Heterocellular Coupling

    This abstract was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Seattle, Washington by Crystal L. Sigulinsky, J. Scott Lauritzen, John V. Hoang, Carl B. Watt, Bryan W. Jones, James R. Anderson, Shoeb Mohammed and Robert E. Marc.

    May 6, 2013 — Read more No Comments
  25. Building Retinal Connectomes

    There has been quite a bit of discussion of connectomes in the last while with President Obama’s new BRAIN initiative.  It is important to consider some of the requirements of obtaining a true synapse level wiring map in the brain as many are articulating from this initiative.  While there are new technologies that will be […]

    Apr 22, 2013 — Read more No Comments