Kirill Martemyanov, Associate Professor at the Scripps Institute will be delivering a seminar on Molecular Organization of the First Visual Synapse, on Wednesday, February 10th at 12pm in the Moran Eye Center auditorium.
Abstract: Signaling in the retina plays an essential role in our vision. Light is detected by rod and cone photoreceptors that convert it to the electrical response further propagated through the retina circuitry by means of synaptic communication between neurons. To be able to see at low light levels, highly sensitive rods must faithfully transmit the signal that they generate to downstream bipolar neurons. The efforts in my laboratory are focused on studying molecular players and signaling events at the first visual synapse between formed by rod photoreceptors. I will describe how multiple elements of the synaptic signaling machinery are organized and scaffolded together to ensure proper transmission of signal generated by rods enabling vision at low light.