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Preventing Vision Loss in Murine Diabetes by Vascular Stabilization

This poster was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Ft. Lauderdale, Florida by Judd M. Cahoon, Hironori Uehara, Ling Luo, Jacquelyn M. Simonis, Britt Dubil, Tadashi Miya, Paul R. Olson, Kortnie Walker, Bonnie Archer, Peter Barabas, David Krizaj, Gou Young Koh, Guangping Gao and Balamurali K. Ambati.  Full size poster can be seen here.

 

 

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Splicing Shift From Membrane Bound VEGF Receptor 2 to Soluble VEGFR2 Using Morpholino Oligomer Suppresses Suture Induced Corneal Angiogenesis and Lumphangiogenesis and Suppresses Corneal Graft Rejection

This poster was presented today at the Association for Research in Vision and Opthalmology (ARVO) meetings in Ft. Lauderdale, Florida by Hironori Uehara, YangKyung Cho, Jackie Simonis, Judd Cahoon, Bonnie Archer, Ling Luo, Subrata K. Das, Nirbhai Singh and Balamurali K. Ambati.  Full size poster can be seen here.

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Notable Paper: Increased Expression of Multifunctional Serine Protease, HTRA1, in Retinal Pigment Epithelium Induces Polypoidal Choroidal Vasculopathy

Efforts to explore chromosome 10q26, a major candidate region associated with age-related macular degeneration (AMD) have proven difficult and controversial.  This particular region of interest is two neighboring genes, ARMS2 and HTRA1.  However, efforts in trying to explore the functional involvement of either HTRA1 or ARMS2 in AMD have proven to be difficult and have often yielded conflicting results.

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