The University of Utah Department of Ophthalmology and Visual Sciences invites applications for a full-time position at the level of Assistant/Associate Professor (commensurate w/experience) in the field of visual system function and or/disease. Successful candidates are expected to establish a strong research program funded by federal sources (NIH, NSF), to strengthen the current research carried out at the Moran Eye Institute as well as bring new areas of research into focus.
The Moran Eye Center travels globally as one of their missions for International Outreach and provides eye care in remote places around the world that are medically underserved from an ophthalmology perspective.
This is a short video showing the Moran Eye Center setting up an eyecamp in Salma, Guatemala on Dec. 9th. This includes moving furniture at the detination, cleaning, and setting up surgical equipment, operating tables, microscopes, and other allied equipment. This effort involves months of planning and ultimately the goal is to improve or restore vision in over 250 patients who travel from all over Guatemala to receive free care.
The Paul Kayser International Award in Retina Research was created by the Directors of Retina Research Foundation and endowed by the Trustees of The Kayser Foundation to honor and perpetuate the memory of long-time friend and dedicated benefactor of RRF, Paul Kayser. Through this award both organizations are demonstrating the conviction they shared with Mr. Kayser that blindness caused by retinal disease is a global concern and must be addressed accordingly. It is thus the purpose of this award to foster greater awareness of the need for intensive study of the retina, its role in the visual process, and the retinal diseases that threaten and/or destroy eyesight by recognizing outstanding achievement and sustaining meritorious scientific investigations worldwide.
Dr. Marc was chosen as the recipient of this award for his lifetime body of work in retinal research, discovering the structure and function of the retina through novel technologies and approaches that have pushed our understanding of the retina forward.
Clay Radke, Professor of Chemical Engineering and Vision Science at University of California, Berkeley (lab page here) will be delivering a seminar, Topical Ophthalmic Drug Delivery on September 23rd, 2013 at 4:00pm in the John A. Moran Eye Center auditorium.
Despite considerable inefficiency, topical ophthalmic drug delivery remains the main application modality to the human eye. We present a new description of tear dynamics that quantifies tear salinity and drug bioavailability by topical administration. The tear supply/drainage system is divided into 5 compartments: upper and lower menisci, upper and lower conjunctival sacs, and tear film. Transient description is provided for each compartment for tear, salinity, and drug. Compartments are coupled to each other and to drug pharmacokinetics (PK) through kinetic routes. Salinity must be accounted for in PK models because osmotic flow is drawn from the cornea/conjunctiva into tear thus diluting the drug. Osmotic water flow through the cornea and conjunctiva contribute 20 to 50 % to the total tear supply. Tear salinity is also critical to dry eye. Predicted tear osmolarity, volume, and tear turnover rates all match available clinical measurements. Drug bioavailability is surprisingly independent of supplied drop volume and viscosity. In spite of this, 30 to 90% of drug is lost to drainage through the punctum depending on specific drug transport and reactive properties. Order of addition of mixed drugs is also found important.
We mentioned some of the outreach work that the Moran Eye Center does a few posts ago. There is now a documentary, Duk County (trailer linked in the above video) about the humanitarian expedition to South Sudan to restore vision to those who have lost it through cataracts and trachoma mediated blindness. There is also a link and article from National Geographic Adventure Blog here.
The Moran Eye Center‘s first eye intervention in South Sudan is documented in that film, but our Alan S. Crandall, MD, and Dr. Charles Weber, MD, recently completed a second major ophthalmic medical mission to South Sudan. As part of a life-changing five-year initiative, the team once again traveled to the war-torn region to provide eye surgeries to the visually impaired with a small medical team, carrying in every single supply, from Q-tips to microscopes. Through the efforts of Drs. Crandall and Weber, they helped restore sight to 325 patients with cataracts and trachoma.
After finding cataracts far more advanced than expected on their 2011 mission, the team returned in 2012 with a hand-held ultrasound machine that allows them to see into the back of the eye no matter how opaque the front of the eye is during the initial screening. “The clinic in South Sudan is quite bare, but we are able to bring all the supplies we need in order to successfully operate on patients. Last year, we operated as bats flew around our heads and relied on a generator that didn’t always work. Fortunately, there is a new operating room that better suits the needs of the patients,” said Crandall. Continue reading “Duk County And Moran Eye Center Outreach At Home And Abroad”
Choroidal neoplasms are tumors of the choroid of the eye. The most common intraocular tumors are in fact, malignant melanomas of the choroid which increase in frequency as we age. Continue reading “Choroidal Neoplasm”
Here on Webvision, our goal is retinal education and even though Webvision is hosted here at the Moran Eye Center, we nevertheless try to include as much of the wider community as possible in posts and in content, though we will point out work that comes of of the Moran Eye Center from time to time. So, while we compiling chapters for information as well as posts to the front page here that we hope contain informative items relevant to the retina and the retinal research community, it is important from time to time to step back and ask why it is that we study the retina and get a bigger picture view of what role all of this biology plays in peoples lives.
Grand Rounds for today is an interesting finding of an anomalous congenital blood vessel that crosses the front of a pupil, relaxing when the pupil is small, and pulling taut when the pupil becomes is dilated. The image above is relaxed with a small pupil.
Dr. Gregory Hageman, Executive Director of the Center for Translational Medicine (CTM) at the John A. Moran Eye Center at the University of Utah related in his address that AMD consists of multiple biological diseases. Dr. Hageman continued by expressing that a convergence of clinical, biological and genetic data has led to a stronger understanding of the disease and new hope for the development of diagnostics and therapeutic interventions currently underway.
We are on our way to ARVO, 2012! ARVO is an annual meeting of researchers and clinicians who’s focus is on the visual system.
As happened last year, over the next few days, you will see some of our research abstracts appear on Webvision as the presentations are completed at ARVO. We hope that it will provide an insight into some of the work that goes on here at the Moran Eye Center as well as our commitment to understand the basic science of vision and cure blinding diseases.
If you are going to be at ARVO and want to meet up, leave us a comment here or send a Tweet to @BWJones. We might even be able to work you into the Moran social on Monday the 7th…